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Methadone is indicated for the preservation treatment of opioid dependence (i.e. opioid use disorder per the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM).

A 2009 Cochran e review found that it was effective in keeping people in treatment and in the reduction or cessation of heroin use as measured by self-report and hair/urine analysis but did not affect criminal function or risk of death. Want Pain Relief medication? 

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The treatment of opioid-dependent persons with it will follow one of two routes. It maintenance therapy (MMT) is prescribed to individuals who wish to abstain from illicit drug use but have failed to continue abstinence from opioids for significant periods.

The duration of its maintenance ranges from a few months to lifelong. It reduction programs are suitable for addicted persons who wish to completely stop using drugs.

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The length of the reduction program will depend on the starting dose and speed of reduction, this varies between clinics and from one person to another person.

In addition, enrollment in its maintenance has the potential to decrease the transmission of infectious diseases associated with opiate injection, such as hepatitis and HIV. Want Pain Relief medication?

The principal goals of its maintenance are to relieve opioid cravings, suppress the abstinence syndrome, and block the euphoric effects associated with opioids.

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However, its abuse does contain the potential for dependence. When used rightly, methadone maintenance has been found to be medically safe and non-sedating and provides a slow recovery from opioid addiction.

It is also indicated for pregnant women addicted to opioids. Want Pain Relief medication?

Adverse effects:

Low Blood Pressure
Diarrhea or constipation
Sleep problems such as drowsiness, trouble falling
Perspiration and sweating
asleep (Insomnia), and trouble staying asleep
Dizziness or fainting
Mood changes, euphoria, disorientation
Heart intolerance
Constricted pupils
Dry mouth
Nausea and vomiting
Chronic fatigue, sleepiness, and exhaustion
Difficulty urinating
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